PI3K/Akt Pathway: A Role in δ-Opioid Receptor–Mediated RGC Neuroprotection

PURPOSE: This study examines the role of PI3K/Akt pathway in δ-opioid receptor agonist (SNC-121)-induced RGC neuroprotection in a chronic glaucoma rat model. METHODS: Injecting hypertonic saline into the limbal veins of Brown Norway rats elevated IOP. Rats were treated either with 1 mg/kg SNC-121 or...

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Detalles Bibliográficos
Autores principales: Husain, Shahid, Ahmad, Anis, Singh, Sudha, Peterseim, Carolyn, Abdul, Yasir, Nutaitis, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Physiology and Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749243/
https://www.ncbi.nlm.nih.gov/pubmed/29288267
http://dx.doi.org/10.1167/iovs.16-20673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749243/
https://www.ncbi.nlm.nih.gov/pubmed/29288267
http://dx.doi.org/10.1167/iovs.16-20673

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