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NRF2 Regulates HER1 Signaling Pathway to Modulate the Sensitivity of Ovarian Cancer Cells to Lapatinib and Erlotinib

NF-E2-related factor 2 (NRF2) regulates the transcription of a battery of metabolic and cytoprotective genes. NRF2 and epidermal growth factor receptors (EGFRs/HERs) are regulators of cellular proliferation and determinants of cancer initiation and progression. NRF2 and HERs confer cancers with resi...

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Detalles Bibliográficos
Autores principales: Kankia, Ibrahim H., Khalil, Hilal S., Langdon, Simon P., Moult, Peter R., Bown, James L., Deeni, Yusuf Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749283/
https://www.ncbi.nlm.nih.gov/pubmed/29410730
http://dx.doi.org/10.1155/2017/1864578