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Irf4-dependent CD103(+)CD11b(+) dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileus

OBJECTIVE: Postoperative ileus (POI), the most frequent complication after intestinal surgery, depends on dendritic cells (DCs) and macrophages. Here, we have investigated the mechanism that activates these cells and the contribution of the intestinal microbiota for POI induction. DESIGN: POI was in...

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Detalles Bibliográficos
Autores principales: Pohl, Judith-Mira, Gutweiler, Sebastian, Thiebes, Stephanie, Volke, Julia K, Klein-Hitpass, Ludger, Zwanziger, Denise, Gunzer, Matthias, Jung, Steffen, Agace, William W, Kurts, Christian, Engel, Daniel Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Gut 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749346/
https://www.ncbi.nlm.nih.gov/pubmed/28615301
http://dx.doi.org/10.1136/gutjnl-2017-313856