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Inhibition of 5-lipoxygenase inhibitor zileuton in high-fat diet-induced nonalcoholic fatty liver disease progression model

OBJECTIVE(S): Arachidonic Acid/5-lipoxygenase (AA/5-LOX) pathway connects lipid metabolism and proinflammatory cytokine, which are both related to the development and progression of nonalcoholic fatty liver disease (NAFLD). Therefore, the present study was designed to investigate the role of AA/5-LO...

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Detalles Bibliográficos
Autores principales: Ma, Kuifen, Chen, Yihe, Liang, Xingguang, Miao, Jing, Zhao, Qingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749354/
https://www.ncbi.nlm.nih.gov/pubmed/29299197
http://dx.doi.org/10.22038/IJBMS.2017.9482