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Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease

OBJECTIVE: An inadequate host response to the intestinal microbiota likely contributes to the manifestation and progression of human inflammatory bowel disease (IBD). However, molecular approaches to unravelling the nature of the defective crosstalk and its consequences for intestinal metabolic and...

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Detalles Bibliográficos
Autores principales: Häsler, Robert, Sheibani-Tezerji, Raheleh, Sinha, Anupam, Barann, Matthias, Rehman, Ateequr, Esser, Daniela, Aden, Konrad, Knecht, Carolin, Brandt, Berenice, Nikolaus, Susanna, Schäuble, Sascha, Kaleta, Christoph, Franke, Andre, Fretter, Christoph, Müller, Werner, Hütt, Marc-Thorsten, Krawczak, Michael, Schreiber, Stefan, Rosenstiel, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749366/
https://www.ncbi.nlm.nih.gov/pubmed/27694142
http://dx.doi.org/10.1136/gutjnl-2016-311651