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Preparation of anastrozole loaded PEG-PLA nanoparticles: evaluation of apoptotic response of breast cancer cell lines

PURPOSE: Anastrozole (ANS) is an aromatase inhibitor that is widely used as a treatment for breast cancer in postmenopausal women. Despite the wide use of ANS, it is associated with serious side effects due to uncontrolled delivery. In addition, ANS exhibits low solubility and short plasma half-life...

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Detalles Bibliográficos
Autores principales: Alyafee, Yusra A, Alaamery, Manal, Bawazeer, Shahad, Almutairi, Mansour S, Alghamdi, Badr, Alomran, Nawaf, Sheereen, Atia, Daghestani, Maha, Massadeh, Salam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749378/
https://www.ncbi.nlm.nih.gov/pubmed/29343958
http://dx.doi.org/10.2147/IJN.S151139