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Preparation of anastrozole loaded PEG-PLA nanoparticles: evaluation of apoptotic response of breast cancer cell lines
PURPOSE: Anastrozole (ANS) is an aromatase inhibitor that is widely used as a treatment for breast cancer in postmenopausal women. Despite the wide use of ANS, it is associated with serious side effects due to uncontrolled delivery. In addition, ANS exhibits low solubility and short plasma half-life...
Autores principales: | Alyafee, Yusra A, Alaamery, Manal, Bawazeer, Shahad, Almutairi, Mansour S, Alghamdi, Badr, Alomran, Nawaf, Sheereen, Atia, Daghestani, Maha, Massadeh, Salam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749378/ https://www.ncbi.nlm.nih.gov/pubmed/29343958 http://dx.doi.org/10.2147/IJN.S151139 |
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