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The influence of CYP3A5 polymorphisms on haloperidol treatment in patients with alcohol addiction

BACKGROUND: Isoenzymes CYP2D6 and CYP3A4, the activity of which varies widely, are involved in metabolism of haloperidol and may influence its profile of efficacy and safety. OBJECTIVE: The primary aim of this study was to estimate the relationship between CYP3A5 gene polymorphism, activity of the C...

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Detalles Bibliográficos
Autores principales: Zastrozhin, Mikhail Sergeevich, Grishina, Elena Anatolievna, Ryzhikova, Kristina Anatolievna, Smirnov, Valery Valerievich, Savchenko, Ludmila Mikhailovna, Bryun, Evgeny Alekseevich, Sychev, Dmitry Alekseevich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749387/
https://www.ncbi.nlm.nih.gov/pubmed/29343979
http://dx.doi.org/10.2147/PGPM.S144503