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The influence of CYP3A5 polymorphisms on haloperidol treatment in patients with alcohol addiction
BACKGROUND: Isoenzymes CYP2D6 and CYP3A4, the activity of which varies widely, are involved in metabolism of haloperidol and may influence its profile of efficacy and safety. OBJECTIVE: The primary aim of this study was to estimate the relationship between CYP3A5 gene polymorphism, activity of the C...
Autores principales: | Zastrozhin, Mikhail Sergeevich, Grishina, Elena Anatolievna, Ryzhikova, Kristina Anatolievna, Smirnov, Valery Valerievich, Savchenko, Ludmila Mikhailovna, Bryun, Evgeny Alekseevich, Sychev, Dmitry Alekseevich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749387/ https://www.ncbi.nlm.nih.gov/pubmed/29343979 http://dx.doi.org/10.2147/PGPM.S144503 |
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