The oral bioavailability, excretion and cytochrome P450 inhibition properties of epiberberine: an in vivo and in vitro evaluation

Epiberberine (EPI) is a novel and potentially effective therapeutic and preventive agent for diabetes and cardiovascular disease. To evaluate its potential value for drug development, a specific, sensitive and robust high-performance liquid chromatography-tandem mass spectrometry assay for the deter...

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Detalles Bibliográficos
Autores principales: Chen, Ning, Yang, Xiao-yan, Guo, Chang-e, Bi, Xin-ning, Chen, Jian-hua, Chen, Hong-ying, Li, Hong-pin, Lin, Hong-ying, Zhang, Yu-jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749554/
https://www.ncbi.nlm.nih.gov/pubmed/29343943
http://dx.doi.org/10.2147/DDDT.S151660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749554/
https://www.ncbi.nlm.nih.gov/pubmed/29343943
http://dx.doi.org/10.2147/DDDT.S151660

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