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Peripheral and spinal TRPA1 channels contribute to formalin-induced long-lasting mechanical hypersensitivity
BACKGROUND: Transient receptor potential ankyrin 1 (TRPA1) is a non-selective cation channel expressed by a subset of nociceptive neurons that acts as a multimodal receptor. Its activity contributes to modulate nociceptive transmission in acute inflammatory pain. However, the role of this channel in...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749559/ https://www.ncbi.nlm.nih.gov/pubmed/29343980 http://dx.doi.org/10.2147/JPR.S153671 |