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Peripheral and spinal TRPA1 channels contribute to formalin-induced long-lasting mechanical hypersensitivity

BACKGROUND: Transient receptor potential ankyrin 1 (TRPA1) is a non-selective cation channel expressed by a subset of nociceptive neurons that acts as a multimodal receptor. Its activity contributes to modulate nociceptive transmission in acute inflammatory pain. However, the role of this channel in...

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Detalles Bibliográficos
Autores principales: Martínez-Rojas, Vladimir A, García, Guadalupe, Noriega-Navarro, Roxana, Guzmán-Priego, Crystell G, Torres-López, Jorge E, Granados-Soto, Vinicio, Murbartián, Janet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749559/
https://www.ncbi.nlm.nih.gov/pubmed/29343980
http://dx.doi.org/10.2147/JPR.S153671