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Antitumor effect of a new nano-vector with miRNA-135a on malignant glioma

INTRODUCTION: MiR-135a is found to selectively induce apoptosis in glioma cell but not in normal neurons and glial cells. However, low transfection efficacy limits its application in vivo as other miRNAs. We prepared a new kind of nano-vector based on polyethylene glycol methyl ether (mPEG) and hype...

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Detalles Bibliográficos
Autores principales: Liang, Chaofeng, Sun, Weitong, He, Haiyong, Zhang, Baoyu, Ling, Cong, Wang, Bocheng, Huang, Tengchao, Hou, Bo, Guo, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749566/
https://www.ncbi.nlm.nih.gov/pubmed/29343959
http://dx.doi.org/10.2147/IJN.S148142