Glioma-induced SIRT1-dependent activation of hMOF histone H4 lysine 16 acetyltransferase in microglia promotes a tumor supporting phenotype

High-grade gliomas are malignant aggressive primary brain tumors with limited therapeutic options, and dismal prognosis for patients. Microglia, the resident immune cells of the brain, are recruited and reprogrammed into tumor-supporting cells by glioma cells, which in turn positively influence tumo...

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Detalles Bibliográficos
Autores principales: Saidi, Dalel, Cheray, Mathilde, Osman, Ahmed M., Stratoulias, Vassilis, Lindberg, Olle R., Shen, Xianli, Blomgren, Klas, Joseph, Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749650/
https://www.ncbi.nlm.nih.gov/pubmed/29308302
http://dx.doi.org/10.1080/2162402X.2017.1382790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749650/
https://www.ncbi.nlm.nih.gov/pubmed/29308302
http://dx.doi.org/10.1080/2162402X.2017.1382790

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