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Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice

Presence of tubulointerstitial fibrosis is predictive of progressive decline in kidney function, independent of its underlying cause. Injury to the renal microvasculature is a major factor in the progression of fibrosis and identification of factors that regulate endothelium in fibrosis is desirable...

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Detalles Bibliográficos
Autores principales: Loganathan, Krishnapriya, Salem Said, Ebtisam, Winterrowd, Emily, Orebrand, Martina, He, Liqun, Vanlandewijck, Michael, Betsholtz, Christer, Quaggin, Susan E., Jeansson, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749705/
https://www.ncbi.nlm.nih.gov/pubmed/29293543
http://dx.doi.org/10.1371/journal.pone.0189433