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Elp3 and RlmN: A tale of two mitochondrial tail-anchored radical SAM enzymes in Toxoplasma gondii

Radical S-adenosylmethionine (rSAM) enzymes use a 5’-deoxyadensyl 5’-radical to methylate a wide array of diverse substrates including proteins, lipids and nucleic acids. One such enzyme, Elongator protein-3 (TgElp3), is an essential protein in Toxoplasma gondii, a protozoan parasite that can cause...

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Detalles Bibliográficos
Autores principales: Padgett, Leah R., Lentini, Jenna M., Holmes, Michael J., Stilger, Krista L., Fu, Dragony, Sullivan, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749711/
https://www.ncbi.nlm.nih.gov/pubmed/29293520
http://dx.doi.org/10.1371/journal.pone.0189688