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Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progression
Cancer results from alterations at essential genomic sites and is characterized by uncontrolled cell proliferation, invasion and metastasis. Identification of driver genes of metastatic progression is essential, as metastases, not primary tumors, are fatal. To gain insight into the mutational concor...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749725/ https://www.ncbi.nlm.nih.gov/pubmed/29293529 http://dx.doi.org/10.1371/journal.pone.0189887 |