Reduced telomere length is associated with fibrotic joint disease suggesting that impaired telomere repair contributes to joint fibrosis

OBJECTIVE: Joint fibrosis affects many synovial joints (including hip, knee and shoulder) causing stiffness and pain. The mechanism of joint fibrosis remains unknown, although genetic factors may contribute. Defects in maintenance of telomere length resulting from impaired telomere repair have been...

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Detalles Bibliográficos
Autores principales: Kalson, Nicholas S., Brock, Tim M., Mangino, Massimo, Fabiane, Stella M., Mann, Derek A., Borthwick, Lee A., Deehan, David J., Williams, Frances M. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749754/
https://www.ncbi.nlm.nih.gov/pubmed/29293561
http://dx.doi.org/10.1371/journal.pone.0190120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749754/
https://www.ncbi.nlm.nih.gov/pubmed/29293561
http://dx.doi.org/10.1371/journal.pone.0190120

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