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MicroRNAs miR-19, miR-340, miR-374 and miR-542 regulate MID1 protein expression
The MID1 ubiquitin ligase activates mTOR signaling and regulates mRNA translation. Misregulation of MID1 expression is associated with various diseases including midline malformation syndromes, cancer and neurodegenerative diseases. While this indicates that MID1 expression must be tightly regulated...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749791/ https://www.ncbi.nlm.nih.gov/pubmed/29293623 http://dx.doi.org/10.1371/journal.pone.0190437 |