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MicroRNAs miR-19, miR-340, miR-374 and miR-542 regulate MID1 protein expression

The MID1 ubiquitin ligase activates mTOR signaling and regulates mRNA translation. Misregulation of MID1 expression is associated with various diseases including midline malformation syndromes, cancer and neurodegenerative diseases. While this indicates that MID1 expression must be tightly regulated...

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Detalles Bibliográficos
Autores principales: Unterbruner, Kristoffer, Matthes, Frank, Schilling, Judith, Nalavade, Rohit, Weber, Stephanie, Winter, Jennifer, Krauß, Sybille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749791/
https://www.ncbi.nlm.nih.gov/pubmed/29293623
http://dx.doi.org/10.1371/journal.pone.0190437