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Intravenously delivered mesenchymal stem cell-derived exosomes target M2-type macrophages in the injured spinal cord

In a previous report we showed that intravenous infusion of bone marrow-derived mesenchymal stem cells (MSCs) improved functional recovery after contusive spinal cord injury (SCI) in the non-immunosuppressed rat, although the MSCs themselves were not detected at the spinal cord injury (SCI) site [1]...

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Detalles Bibliográficos
Autores principales: Lankford, Karen L., Arroyo, Edgardo J., Nazimek, Katarzyna, Bryniarski, Krzysztof, Askenase, Philip W., Kocsis, Jeffery D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749801/
https://www.ncbi.nlm.nih.gov/pubmed/29293592
http://dx.doi.org/10.1371/journal.pone.0190358