Crystal structure of human NLRP12 PYD domain and implication in homotypic interaction

NLRP12 is a NOD-like receptor that plays multiple roles in both inflammation and tumorigenesis. Despite the importance, little is known about its mechanism of action at the molecular level. Here, we report the crystal structure of NLRP12 PYD domain at 1.70 Å fused with an maltose-binding protein (MB...

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Detalles Bibliográficos
Autores principales: Jin, Tengchuan, Huang, Mo, Jiang, Jiansheng, Smith, Patrick, Xiao, Tsan Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749810/
https://www.ncbi.nlm.nih.gov/pubmed/29293680
http://dx.doi.org/10.1371/journal.pone.0190547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749810/
https://www.ncbi.nlm.nih.gov/pubmed/29293680
http://dx.doi.org/10.1371/journal.pone.0190547

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