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Integrated genetic and epigenetic prediction of coronary heart disease in the Framingham Heart Study

An improved method for detecting coronary heart disease (CHD) could have substantial clinical impact. Building on the idea that systemic effects of CHD risk factors are a conglomeration of genetic and environmental factors, we use machine learning techniques and integrate genetic, epigenetic and phe...

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Detalles Bibliográficos
Autores principales: Dogan, Meeshanthini V., Grumbach, Isabella M., Michaelson, Jacob J., Philibert, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749823/
https://www.ncbi.nlm.nih.gov/pubmed/29293675
http://dx.doi.org/10.1371/journal.pone.0190549