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USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation

Correct segregation of the mitotic chromosomes into daughter cells is a highly regulated process critical to safeguard genome stability. During M phase the spindle assembly checkpoint (SAC) ensures that all kinetochores are correctly attached before its inactivation allows progression into anaphase....

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Detalles Bibliográficos
Autores principales: Stockum, Anna, Snijders, Ambrosius P., Maertens, Goedele N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749825/
https://www.ncbi.nlm.nih.gov/pubmed/29293652
http://dx.doi.org/10.1371/journal.pone.0190513