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Optimal number of spacers in CRISPR arrays

Prokaryotic organisms survive under constant pressure of viruses. CRISPR-Cas system provides its prokaryotic host with an adaptive immune defense against viruses that have been previously encountered. It consists of two components: Cas-proteins that cleave the foreign DNA and CRISPR array that suits...

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Detalles Bibliográficos
Autores principales: Martynov, Alexander, Severinov, Konstantin, Ispolatov, Iaroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749868/
https://www.ncbi.nlm.nih.gov/pubmed/29253874
http://dx.doi.org/10.1371/journal.pcbi.1005891