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The pUL37 tegument protein guides alpha-herpesvirus retrograde axonal transport to promote neuroinvasion

A hallmark property of the neurotropic alpha-herpesvirinae is the dissemination of infection to sensory and autonomic ganglia of the peripheral nervous system following an initial exposure at mucosal surfaces. The peripheral ganglia serve as the latent virus reservoir and the source of recurrent inf...

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Detalles Bibliográficos
Autores principales: Richards, Alexsia L., Sollars, Patricia J., Pitts, Jared D., Stults, Austin M., Heldwein, Ekaterina E., Pickard, Gary E., Smith, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749899/
https://www.ncbi.nlm.nih.gov/pubmed/29216315
http://dx.doi.org/10.1371/journal.ppat.1006741