The amino-terminus of the hepatitis C virus (HCV) p7 viroporin and its cleavage from glycoprotein E2-p7 precursor determine specific infectivity and secretion levels of HCV particle types

Viroporins are small transmembrane proteins with ion channel activities modulating properties of intracellular membranes that have diverse proviral functions. Hepatitis C virus (HCV) encodes a viroporin, p7, acting during assembly, envelopment and secretion of viral particles (VP). HCV p7 is release...

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Detalles Bibliográficos
Autores principales: Denolly, Solène, Mialon, Chloé, Bourlet, Thomas, Amirache, Fouzia, Penin, François, Lindenbach, Brett, Boson, Bertrand, Cosset, François-Loïc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749900/
https://www.ncbi.nlm.nih.gov/pubmed/29253880
http://dx.doi.org/10.1371/journal.ppat.1006774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749900/
https://www.ncbi.nlm.nih.gov/pubmed/29253880
http://dx.doi.org/10.1371/journal.ppat.1006774

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