Cargando…

The amino-terminus of the hepatitis C virus (HCV) p7 viroporin and its cleavage from glycoprotein E2-p7 precursor determine specific infectivity and secretion levels of HCV particle types

Viroporins are small transmembrane proteins with ion channel activities modulating properties of intracellular membranes that have diverse proviral functions. Hepatitis C virus (HCV) encodes a viroporin, p7, acting during assembly, envelopment and secretion of viral particles (VP). HCV p7 is release...

Descripción completa

Detalles Bibliográficos
Autores principales:	Denolly, Solène, Mialon, Chloé, Bourlet, Thomas, Amirache, Fouzia, Penin, François, Lindenbach, Brett, Boson, Bertrand, Cosset, François-Loïc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749900/ https://www.ncbi.nlm.nih.gov/pubmed/29253880 http://dx.doi.org/10.1371/journal.ppat.1006774

Ejemplares similares

HCV Interplay with Lipoproteins: Inside or Outside the Cells?
por: Cosset, François-Loïc, et al.
Publicado: (2020)

Overview of HCV Life Cycle with a Special Focus on Current and Possible Future Antiviral Targets
por: Alazard-Dany, Nathalie, et al.
Publicado: (2019)

Nup98 Is Subverted from Annulate Lamellae by Hepatitis C Virus Core Protein to Foster Viral Assembly
por: Boson, Bertrand, et al.
Publicado: (2022)

Enveloped viruses distinct from HBV induce dissemination of hepatitis D virus in vivo
por: Perez-Vargas, Jimena, et al.
Publicado: (2019)

Low-density hepatitis C virus infectious particles are protected from oxidation by secreted cellular proteins
por: Granier, Christelle, et al.
Publicado: (2023)

A Concerted Action of Hepatitis C Virus P7 and Nonstructural Protein 2 Regulates Core Localization at the Endoplasmic Reticulum and Virus Assembly
por: Boson, Bertrand, et al.
Publicado: (2011)

The SARS-CoV-2 envelope and membrane proteins modulate maturation and retention of the spike protein, allowing assembly of virus-like particles
por: Boson, Bertrand, et al.
Publicado: (2020)

Structural and Functional Properties of the Hepatitis C Virus p7 Viroporin
por: Madan, Vanesa, et al.
Publicado: (2015)

Hepatitis C virus sequence divergence preserves p7 viroporin structural and dynamic features
por: Oestringer, Benjamin P., et al.
Publicado: (2019)

A fusion peptide in preS1 and the human protein disulfide isomerase ERp57 are involved in hepatitis B virus membrane fusion process
por: Pérez-Vargas, Jimena, et al.
Publicado: (2021)

Ion channel activity of the CSFV p7 viroporin in surrogates of the ER lipid bilayer
por: Largo, Eneko, et al.
Publicado: (2016)

Computational modeling of the p7 monomer from HCV and its interaction with small molecule drugs
por: Wang, Yi-Ting, et al.
Publicado: (2013)

SPCS1-Dependent E2-p7 processing determines HCV Assembly efficiency
por: Alzahrani, Nabeel, et al.
Publicado: (2022)

Genotype-specific differences in structural features of hepatitis C virus (HCV) p7 membrane protein
por: Kalita, Monoj Mon, et al.
Publicado: (2015)

Hepatitis C Virus P7—A Viroporin Crucial for Virus Assembly and an Emerging Target for Antiviral Therapy
por: Steinmann, Eike, et al.
Publicado: (2010)

Preliminary Evidence for Hepatitis Delta Virus Exposure in Patients Who Are Apparently Not Infected With Hepatitis B Virus
por: Chemin, Isabelle, et al.
Publicado: (2021)

Prohibitin is overexpressed in Huh-7-HCV and Huh-7.5-HCV cells harboring in vitro transcribed full-length hepatitis C virus RNA
por: Dang, Shuang-Suo, et al.
Publicado: (2011)

Report of One-Year Prospective Surveillance of SARS-CoV-2 in Dogs and Cats in France with Various Exposure Risks: Confirmation of a Low Prevalence of Shedding, Detection and Complete Sequencing of an Alpha Variant in a Cat
por: Krafft, Emilie, et al.
Publicado: (2021)

Viroporins
por: Hyser, Joseph M.
Publicado: (2015)

The interplays between Crimean-Congo hemorrhagic fever virus (CCHFV) M segment-encoded accessory proteins and structural proteins promote virus assembly and infectivity
por: Freitas, Natalia, et al.
Publicado: (2020)

Lower ribavirin biodisponibility in patients with HIV-HCV coinfection in comparison with HCV monoinfected patients
por: Hatu, Giorgiana, et al.
Publicado: (2014)

HCV core antigen and HCV-RNA in HIV/HCV co-infected patients with different HCV genotypes
por: Garbuglia, Anna Rosa, et al.
Publicado: (2014)

A longitudinal study of SARS-CoV-2-infected patients reveals a high correlation between neutralizing antibodies and COVID-19 severity
por: Legros, Vincent, et al.
Publicado: (2021)

The correlation of HCV RNA and HCV core antigen in different genotypes of HCV
por: Xiang, Yu, et al.
Publicado: (2018)

miR-122 and Ago interactions with the HCV genome alter the structure of the viral 5′ terminus
por: Chahal, Jasmin, et al.
Publicado: (2019)

HCV and Oxidative Stress: Implications for HCV Life Cycle and HCV-Associated Pathogenesis
por: Medvedev, Regina, et al.
Publicado: (2016)

Significant Redox Insensitivity of the Functions of the SARS-CoV Spike Glycoprotein: COMPARISON WITH HIV ENVELOPE
por: Lavillette, Dimitri, et al.
Publicado: (2006)

Induction of neutralising antibodies by virus-like particles harbouring surface proteins from highly pathogenic H5N1 and H7N1 influenza viruses
por: Szécsi, Judit, et al.
Publicado: (2006)

Symmetric dimeric adamantanes for exploring the structure of two viroporins: influenza virus M2 and hepatitis C virus p7
por: Mandour, Yasmine M, et al.
Publicado: (2018)

HCV and lichen planus: HCV and lichen planus
por: Rebora, Alfredo
Publicado: (2011)

The p7 Protein of Hepatitis C Virus Forms Structurally Plastic, Minimalist Ion Channels
por: Chandler, Danielle E., et al.
Publicado: (2012)

Death by viroporin
por: Jones, Susan
Publicado: (2007)

Receptor Complementation and Mutagenesis Reveal SR-BI as an Essential HCV Entry Factor and Functionally Imply Its Intra- and Extra-Cellular Domains
por: Dreux, Marlène, et al.
Publicado: (2009)

Effect of combined siRNA of HCV E2 gene and HCV receptors against HCV
por: Jahan, Shah, et al.
Publicado: (2011)

In Depth Analysis on the Binding Sites of Adamantane Derivatives in HCV (Hepatitis C Virus) p7 Channel Based on the NMR Structure
por: Du, Qi-Shi, et al.
Publicado: (2014)

Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy
por: Shaw, Joseph, et al.
Publicado: (2020)

The p7 protein of the hepatitis C virus induces cell death differently from the influenza A virus viroporin M2
por: Aweya, Jude Juventus, et al.
Publicado: (2013)

Optimized Hepatitis C Virus (HCV) E2 Glycoproteins and their Immunogenicity in Combination with MVA-HCV
por: Marín, María Q., et al.
Publicado: (2020)

P292: HCV transmission in a gastroenterology endoscopy unit
por: Caballero, M Cantero, et al.
Publicado: (2013)

Hepatitis C Virus p7 Protein Is Crucial for Assembly and Release of Infectious Virions
por: Steinmann, Eike, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_iu1h0a16dh2c0ihfjt8nrrairt