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Pro-tumorigenic roles of TGF-β signaling during the early stages of liver tumorigenesis through upregulation of Snail

Many studies have focused on the tumor suppressive role of TGF-β signaling during the early stages of tumorigenesis by activating the target genes involved in cytostasis and apoptosis. We investigated the effects of TGF-β inhibition on early tumorigenesis in the liver, by employing diverse inhibitor...

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Detalles Bibliográficos
Autores principales: Moon, Hyuk, Han, Kwang-Hyub, Ro, Simon Weonsang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749904/
https://www.ncbi.nlm.nih.gov/pubmed/29065973
http://dx.doi.org/10.5483/BMBRep.2017.50.12.201