Effects of Vacuolar H(+)-ATPase Inhibition on Activation of Cathepsin B and Cathepsin L Secreted from MDA-MB231 Breast Cancer Cells

Studies indicate secreted cathepsins are involved in metastasis. V-ATPases, which are necessary for activating intracellular cathepsins, also play a role in metastasis and are targeted to the plasma membrane of metastatic breast cancer cells. We are interested in a connection between cell surface V-...

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Detalles Bibliográficos
Autores principales: Uhlman, Andrew, Folkers, Kelly, Liston, Jared, Pancholi, Harshida, Hinton, Ayana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750200/
https://www.ncbi.nlm.nih.gov/pubmed/28766149
http://dx.doi.org/10.1007/s12307-017-0196-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750200/
https://www.ncbi.nlm.nih.gov/pubmed/28766149
http://dx.doi.org/10.1007/s12307-017-0196-7

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