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SR 11302, an AP-1 Inhibitor, Reduces Metastatic Lesion Formation in Ex Vivo 4D Lung Cancer Model
Activator protein (AP) -1 is a transcription factor, plays important role in cell differentiation, proliferation and apoptosis. Analysis of tumor cells grown on ex vivo 4D lung cancer model shows increase in components of AP-1, c-Fos and c-Jun in circulating tumor cells (CTC) compared to primary tum...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Netherlands
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750205/ https://www.ncbi.nlm.nih.gov/pubmed/29177791 http://dx.doi.org/10.1007/s12307-017-0202-0 |