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LncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription

Increasing evidence suggests that long noncoding RNAs (lncRNAs) play crucial roles in various biological processes. However, little is known about the effects of lncRNAs on autophagy. Here we report that a lncRNA, termed cardiac autophagy inhibitory factor (CAIF), suppresses cardiac autophagy and at...

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Detalles Bibliográficos
Autores principales: Liu, Cui-Yun, Zhang, Yu-Hui, Li, Rui-Bei, Zhou, Lu-Yu, An, Tao, Zhang, Rong-Cheng, Zhai, Mei, Huang, Yan, Yan, Kao-Wen, Dong, Yan-Han, Ponnusamy, Murugavel, Shan, Chan, Xu, Sheng, Wang, Qi, Zhang, Yan-Hui, Zhang, Jian, Wang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750208/
https://www.ncbi.nlm.nih.gov/pubmed/29295976
http://dx.doi.org/10.1038/s41467-017-02280-y