Cargando…

Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314

The hallmark of many bacterial infections is pain. The underlying mechanisms of pain during live pathogen invasion are not well understood. Here, we elucidate key molecular mechanisms of pain produced during live methicillin-resistant Staphylococcus aureus (MRSA) infection. We show that spontaneous...

Descripción completa

Detalles Bibliográficos
Autores principales: Blake, Kimbria J., Baral, Pankaj, Voisin, Tiphaine, Lubkin, Ashira, Pinho-Ribeiro, Felipe Almeida, Adams, Kelsey L., Roberson, David P., Ma, Yuxin C., Otto, Michael, Woolf, Clifford J., Torres, Victor J., Chiu, Isaac M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750211/
https://www.ncbi.nlm.nih.gov/pubmed/29295977
http://dx.doi.org/10.1038/s41467-017-02448-6