Cargando…
TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis
Although anti-tumor necrosis factor (TNF) agents are highly effective in the treatment of psoriasis, 2–5% of treated patients develop psoriasis-like skin lesions called paradoxical psoriasis. The pathogenesis of this side effect and its distinction from classical psoriasis remain unknown. Here we sh...
Autores principales: | Conrad, Curdin, Di Domizio, Jeremy, Mylonas, Alessio, Belkhodja, Cyrine, Demaria, Olivier, Navarini, Alexander A., Lapointe, Anne-Karine, French, Lars E., Vernez, Maxime, Gilliet, Michel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750213/ https://www.ncbi.nlm.nih.gov/pubmed/29295985 http://dx.doi.org/10.1038/s41467-017-02466-4 |
Ejemplares similares
-
Psoriasis: Classical vs. Paradoxical. The Yin-Yang of TNF and Type I Interferon
por: Mylonas, Alessio, et al.
Publicado: (2018) -
Purpura of the Face and Neck: An Atypical Clinical Presentation Revealing a Hepatosplenic T Cell Lymphoma
por: Kuonen, François, et al.
Publicado: (2014) -
Type I IFNs link skin-associated dysbiotic commensal bacteria to pathogenic inflammation and angiogenesis in rosacea
por: Mylonas, Alessio, et al.
Publicado: (2023) -
Paradoxical psoriasis induced by TNF‐α blockade shows immunological features typical of the early phase of psoriasis development
por: Fania, Luca, et al.
Publicado: (2019) -
Plasmacytoid dendritic cells and regulatory T cells in the tumor microenvironment: A dangerous liaison
por: Conrad, Curdin, et al.
Publicado: (2013)