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Discovery of human cell selective effector molecules using single cell multiplexed activity metabolomics

Discovering bioactive metabolites within a metabolome is challenging because there is generally little foreknowledge of metabolite molecular and cell-targeting activities. Here, single-cell response profiles and primary human tissue comprise a response platform used to discover novel microbial metab...

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Detalles Bibliográficos
Autores principales: Earl, David C., Ferrell, P. Brent, Leelatian, Nalin, Froese, Jordan T., Reisman, Benjamin J., Irish, Jonathan M., Bachmann, Brian O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750220/
https://www.ncbi.nlm.nih.gov/pubmed/29295987
http://dx.doi.org/10.1038/s41467-017-02470-8