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Discovery of human cell selective effector molecules using single cell multiplexed activity metabolomics
Discovering bioactive metabolites within a metabolome is challenging because there is generally little foreknowledge of metabolite molecular and cell-targeting activities. Here, single-cell response profiles and primary human tissue comprise a response platform used to discover novel microbial metab...
Autores principales: | Earl, David C., Ferrell, P. Brent, Leelatian, Nalin, Froese, Jordan T., Reisman, Benjamin J., Irish, Jonathan M., Bachmann, Brian O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750220/ https://www.ncbi.nlm.nih.gov/pubmed/29295987 http://dx.doi.org/10.1038/s41467-017-02470-8 |
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