RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions

In eukaryotes, RAD54 catalyzes branch migration (BM) of Holliday junctions, a basic process during DNA repair, replication, and recombination. RAD54 also stimulates RAD51 recombinase and has other activities. Here, we investigate the structural determinants for different RAD54 activities. We find th...

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Detalles Bibliográficos
Autores principales: Goyal, Nadish, Rossi, Matthew J., Mazina, Olga M., Chi, Yong, Moritz, Robert L., Clurman, Bruce E., Mazin, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750232/
https://www.ncbi.nlm.nih.gov/pubmed/29295984
http://dx.doi.org/10.1038/s41467-017-02497-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750232/
https://www.ncbi.nlm.nih.gov/pubmed/29295984
http://dx.doi.org/10.1038/s41467-017-02497-x

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