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RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions

In eukaryotes, RAD54 catalyzes branch migration (BM) of Holliday junctions, a basic process during DNA repair, replication, and recombination. RAD54 also stimulates RAD51 recombinase and has other activities. Here, we investigate the structural determinants for different RAD54 activities. We find th...

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Detalles Bibliográficos
Autores principales:	Goyal, Nadish, Rossi, Matthew J., Mazina, Olga M., Chi, Yong, Moritz, Robert L., Clurman, Bruce E., Mazin, Alexander V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750232/ https://www.ncbi.nlm.nih.gov/pubmed/29295984 http://dx.doi.org/10.1038/s41467-017-02497-x

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