Amphiphilic nanocarrier-induced modulation of PLK1 and miR-34a leads to improved therapeutic response in pancreatic cancer

The heterogeneity of pancreatic ductal adenocarcinoma (PDAC) suggests that successful treatment might rely on simultaneous targeting of multiple genes, which can be achieved by RNA interference-based therapeutic strategies. Here we show a potent combination of microRNA and siRNA delivered by an effi...

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Detalles Bibliográficos
Autores principales: Gibori, Hadas, Eliyahu, Shay, Krivitsky, Adva, Ben-Shushan, Dikla, Epshtein, Yana, Tiram, Galia, Blau, Rachel, Ofek, Paula, Lee, Joo Sang, Ruppin, Eytan, Landsman, Limor, Barshack, Iris, Golan, Talia, Merquiol, Emmanuelle, Blum, Galia, Satchi-Fainaro, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750234/
https://www.ncbi.nlm.nih.gov/pubmed/29295989
http://dx.doi.org/10.1038/s41467-017-02283-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750234/
https://www.ncbi.nlm.nih.gov/pubmed/29295989
http://dx.doi.org/10.1038/s41467-017-02283-9

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