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Maintaining pH-dependent conformational flexibility of M1 is critical for efficient influenza A virus replication
The M gene segment of influenza A virus has been shown to be a contributing factor to the high growth phenotype. However, it remains largely unknown why matrix protein 1 (M1), the major structural protein encoded by M gene, exhibits pH-dependent conformational changes during virus replication. Under...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750462/ https://www.ncbi.nlm.nih.gov/pubmed/29209052 http://dx.doi.org/10.1038/emi.2017.96 |