Maintaining pH-dependent conformational flexibility of M1 is critical for efficient influenza A virus replication

The M gene segment of influenza A virus has been shown to be a contributing factor to the high growth phenotype. However, it remains largely unknown why matrix protein 1 (M1), the major structural protein encoded by M gene, exhibits pH-dependent conformational changes during virus replication. Under...

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Detalles Bibliográficos
Autores principales: Chiang, Meng-Jung, Musayev, Faik N, Kosikova, Martina, Lin, Zhengshi, Gao, Yamei, Mosier, Philip D, Althufairi, Bashayer, Ye, Zhiping, Zhou, Qibing, Desai, Umesh R, Xie, Hang, Safo, Martin K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750462/
https://www.ncbi.nlm.nih.gov/pubmed/29209052
http://dx.doi.org/10.1038/emi.2017.96

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