Cargando…

Intracellular trafficking of TREM2 is regulated by presenilin 1

Genetic mutations in triggering receptor expressed on myeloid cells 2 (TREM2) have been linked to a variety of neurodegenerative diseases including Alzheimer’s disease, amyotrophic lateral sclerosis, frontotemporal dementia and Parkinson’s disease. In the brain, TREM2 is highly expressed on the cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Yingjun, Li, Xiaoguang, Huang, Timothy, Jiang, Lu-lin, Tan, Zhenqiu, Zhang, Muxian, Cheng, Irene Han-Juo, Wang, Xin, Bu, Guojun, Zhang, Yun-wu, Wang, Qi, Xu, Huaxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750471/
https://www.ncbi.nlm.nih.gov/pubmed/29611543
http://dx.doi.org/10.1038/emm.2017.200