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Empagliflozin Increases Short-Term Urinary Volume Output in Artificially Induced Syndrome of Inappropriate Antidiuresis

OBJECTIVE: Syndrome of inappropriate antidiuresis (SIADH) is the predominant cause of hyponatremia, but treatment options are unsatisfying. SGLT2 inhibitors increase urinary glucose excretion with concomitant osmotic diuresis. We therefore hypothesized SGLT2-inhibitors as a novel treatment for SIADH...

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Detalles Bibliográficos
Autores principales: Refardt, Julie, Winzeler, Bettina, Meienberg, Fabian, Vogt, Deborah R., Christ-Crain, Mirjam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750511/
https://www.ncbi.nlm.nih.gov/pubmed/29422914
http://dx.doi.org/10.1155/2017/7815690