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Competitive Promoter-Associated Matrix Attachment Region Binding of the Arid3a and Cux1 Transcription Factors

Arid3a/Bright/Dril1 is a B cell-specific transactivator that regulates immunoglobulin heavy chain (IgH) gene transcription by binding promoter and enhancer-associated matrix attachment regions (MARs) within the IgH gene locus. Promoter MAR-mediated Arid3a transactivation is antagonized by direct com...

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Detalles Bibliográficos
Autores principales: Kim, Dongkyoon, Schmidt, Christian, Brown, Mark A., Tucker, Haley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750545/
https://www.ncbi.nlm.nih.gov/pubmed/29232859
http://dx.doi.org/10.3390/diseases5040034