Recombinant PrP and Its Contribution to Research on Transmissible Spongiform Encephalopathies

The misfolding of the cellular prion protein (PrP(C)) into the disease-associated isoform (PrP(Sc)) and its accumulation as amyloid fibrils in the central nervous system is one of the central events in transmissible spongiform encephalopathies (TSEs). Due to the proteinaceous nature of the causal ag...

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Detalles Bibliográficos
Autores principales: Charco, Jorge M., Eraña, Hasier, Venegas, Vanessa, García-Martínez, Sandra, López-Moreno, Rafael, González-Miranda, Ezequiel, Pérez-Castro, Miguel Ángel, Castilla, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750591/
https://www.ncbi.nlm.nih.gov/pubmed/29240682
http://dx.doi.org/10.3390/pathogens6040067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750591/
https://www.ncbi.nlm.nih.gov/pubmed/29240682
http://dx.doi.org/10.3390/pathogens6040067

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