Cargando…

Recombinant PrP and Its Contribution to Research on Transmissible Spongiform Encephalopathies

The misfolding of the cellular prion protein (PrP(C)) into the disease-associated isoform (PrP(Sc)) and its accumulation as amyloid fibrils in the central nervous system is one of the central events in transmissible spongiform encephalopathies (TSEs). Due to the proteinaceous nature of the causal ag...

Descripción completa

Detalles Bibliográficos
Autores principales:	Charco, Jorge M., Eraña, Hasier, Venegas, Vanessa, García-Martínez, Sandra, López-Moreno, Rafael, González-Miranda, Ezequiel, Pérez-Castro, Miguel Ángel, Castilla, Joaquín
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750591/ https://www.ncbi.nlm.nih.gov/pubmed/29240682 http://dx.doi.org/10.3390/pathogens6040067

Ejemplares similares

Detection of Pathognomonic Biomarker PrP(Sc) and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases
por: Eraña, Hasier, et al.
Publicado: (2020)

Glycans are not necessary to maintain the pathobiological features of bovine spongiform encephalopathy
por: Otero, Alicia, et al.
Publicado: (2022)

Transmissibility of H-Type Bovine Spongiform Encephalopathy to Hamster PrP Transgenic Mice
por: Okada, Hiroyuki, et al.
Publicado: (2015)

Insights into the Bidirectional Properties of the Sheep–Deer Prion Transmission Barrier
por: Harrathi, Chafik, et al.
Publicado: (2018)

The Glycosylation Status of PrP(C) Is a Key Factor in Determining Transmissible Spongiform Encephalopathy Transmission between Species
por: Wiseman, Frances K., et al.
Publicado: (2015)

Recombinant PrP(Sc) shares structural features with brain-derived PrP(Sc): Insights from limited proteolysis
por: Sevillano, Alejandro M., et al.
Publicado: (2018)

Post-translational modifications in PrP expand the conformational diversity of prions in vivo
por: Aguilar-Calvo, Patricia, et al.
Publicado: (2017)

Prion protein PrP nucleic acid binding and mobilization implicates retroelements as the replicative component of transmissible spongiform encephalopathy
por: Lathe, Richard, et al.
Publicado: (2020)

Sulfated Dextrans Enhance In Vitro Amplification of Bovine Spongiform Encephalopathy PrP(Sc) and Enable Ultrasensitive Detection of Bovine PrP(Sc)
por: Murayama, Yuichi, et al.
Publicado: (2010)

Detection and Localisation of PrP(Sc) in the Liver of Sheep Infected with Scrapie and Bovine Spongiform Encephalopathy
por: Everest, Sally J., et al.
Publicado: (2011)

Protective Effect of Val(129)-PrP against Bovine Spongiform Encephalopathy but not Variant Creutzfeldt-Jakob Disease
por: Fernández-Borges, Natalia, et al.
Publicado: (2017)

A short purification process for quantitative isolation of PrP(Sc) from naturally occurring and experimental transmissible spongiform encephalopathies
por: Polymenidou, Magdalini, et al.
Publicado: (2002)

A Novel, Reliable and Highly Versatile Method to Evaluate Different Prion Decontamination Procedures
por: Eraña, Hasier, et al.
Publicado: (2020)

Immunohistochemical study of PrP(Sc )distribution in neural and extraneural tissues of two cats with feline spongiform encephalopathy
por: Hilbe, Monika M, et al.
Publicado: (2009)

Age and Transmissible Spongiform Encephalopathies
por: Heisey, Dennis M., et al.
Publicado: (2004)

Stability properties of PrP(Sc) from cattle with experimental transmissible spongiform encephalopathies: use of a rapid whole homogenate, protease-free assay
por: Vrentas, Catherine E, et al.
Publicado: (2013)

Protecting effect of PrP codons M142 and K222 in goats orally challenged with bovine spongiform encephalopathy prions
por: Fast, C., et al.
Publicado: (2017)

Transmission of sheep-bovine spongiform encephalopathy to pigs
por: Hedman, Carlos, et al.
Publicado: (2016)

Strain Typing of Classical Scrapie and Bovine Spongiform Encephalopathy (BSE) by Using Ovine PrP (ARQ/ARQ) Overexpressing Transgenic Mice
por: Fatola, Olanrewaju I., et al.
Publicado: (2022)

Involvement of Macrophages in the Pathogenesis of Transmissible Spongiform Encephalopathies
por: Beringue, Vincent, et al.
Publicado: (2002)

Excretion of Transmissible Spongiform Encephalopathy Infectivity in Urine
por: Gregori, Luisa, et al.
Publicado: (2008)

Subcritical Water Hydrolysis Effectively Reduces the In Vitro Seeding Activity of PrP(Sc) but Fails to Inactivate the Infectivity of Bovine Spongiform Encephalopathy Prions
por: Murayama, Yuichi, et al.
Publicado: (2015)

Detection of PrP(res) in peripheral tissue in pigs with clinical disease induced by intracerebral challenge with sheep-passaged bovine spongiform encephalopathy agent
por: Hedman, Carlos, et al.
Publicado: (2018)

Genetic resistance to transmissible spongiform encephalopathies (TSE) in goats
por: Ricci, Antonia, et al.
Publicado: (2017)

Monitoring of clinical signs in goats with transmissible spongiform encephalopathies
por: Konold, Timm, et al.
Publicado: (2010)

Foodborne Transmission of Bovine Spongiform Encephalopathy to Nonhuman Primates
por: Holznagel, Edgar, et al.
Publicado: (2013)

Workshop on Risks Associated with Transmissible Spongiform Encephalopathies (TSEs)
Publicado: (1999)

Increased susceptibility of transgenic mice expressing human PrP to experimental sheep bovine spongiform encephalopathy is not due to increased agent titre in sheep brain tissue
por: Plinston, Chris, et al.
Publicado: (2014)

Use of Murine Bioassay to Resolve Ovine Transmissible Spongiform Encephalopathy Cases Showing a Bovine Spongiform Encephalopathy Molecular Profile
por: Beck, Katy E., et al.
Publicado: (2011)

Detection of PrP(BSE) and prion infectivity in the ileal Peyer’s patch of young calves as early as 2 months after oral challenge with classical bovine spongiform encephalopathy
por: Ackermann, Ivett, et al.
Publicado: (2017)

Rapid Typing of Transmissible Spongiform Encephalopathy Strains with Differential ELISA
por: Simon, Stéphanie, et al.
Publicado: (2008)

Candidate Cell Substrates, Vaccine Production, and Transmissible Spongiform Encephalopathies
por: Piccardo, Pedro, et al.
Publicado: (2011)

Studies of the transmissibility of the agent of bovine spongiform encephalopathy to the domestic chicken
por: Moore, Jo, et al.
Publicado: (2011)

Cerebrospinal fluid biomarkers in human genetic transmissible spongiform encephalopathies
por: Ladogana, Anna, et al.
Publicado: (2009)

Challenges and Advances in Antemortem Diagnosis of Human Transmissible Spongiform Encephalopathies
por: Ascari, Lucas M., et al.
Publicado: (2020)

Generation of a new infectious recombinant prion: a model to understand Gerstmann–Sträussler–Scheinker syndrome
por: Elezgarai, Saioa R., et al.
Publicado: (2017)

Improving the Pharmacological Properties of Ciclopirox for Its Use in Congenital Erythropoietic Porphyria
por: Bernardo-Seisdedos, Ganeko, et al.
Publicado: (2021)

Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model
por: Mestre-Francés, Nadine, et al.
Publicado: (2012)

Heart rate variability analysis in sheep affected by transmissible spongiform encephalopathies
por: Konold, Timm, et al.
Publicado: (2011)

Propagation and Dissemination Strategies of Transmissible Spongiform Encephalopathy Agents in Mammalian Cells
por: Heumüller, Stefanie-Elisabeth, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8rkgtqbr6j283f4bs863ckjav5