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The Development of a Melt-Extruded Shellac Carrier for the Targeted Delivery of Probiotics to the Colon

Hot melt extrusion (HME) is considered an efficient technique in developing solid molecular dispersions, and has been demonstrated to provide sustained, modified and targeted drug delivery resulting in improved bioavailability. However, most commercial enteric or pH-responsive polymers are relativel...

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Detalles Bibliográficos
Autores principales: Gately, Noel M., Kennedy, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750644/
https://www.ncbi.nlm.nih.gov/pubmed/28937621
http://dx.doi.org/10.3390/pharmaceutics9040038