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The Development of a Melt-Extruded Shellac Carrier for the Targeted Delivery of Probiotics to the Colon
Hot melt extrusion (HME) is considered an efficient technique in developing solid molecular dispersions, and has been demonstrated to provide sustained, modified and targeted drug delivery resulting in improved bioavailability. However, most commercial enteric or pH-responsive polymers are relativel...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750644/ https://www.ncbi.nlm.nih.gov/pubmed/28937621 http://dx.doi.org/10.3390/pharmaceutics9040038 |