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Predicting Oral Drug Absorption: Mini Review on Physiologically-Based Pharmacokinetic Models

Most marketed drugs are administered orally, despite the complex process of oral absorption that is difficult to predict. Oral bioavailability is dependent on the interplay between many processes that are dependent on both compound and physiological properties. Because of this complexity, computatio...

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Detalles Bibliográficos
Autores principales: Lin, Louis, Wong, Harvey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750647/
https://www.ncbi.nlm.nih.gov/pubmed/28954416
http://dx.doi.org/10.3390/pharmaceutics9040041