Cargando…
Predicting Oral Drug Absorption: Mini Review on Physiologically-Based Pharmacokinetic Models
Most marketed drugs are administered orally, despite the complex process of oral absorption that is difficult to predict. Oral bioavailability is dependent on the interplay between many processes that are dependent on both compound and physiological properties. Because of this complexity, computatio...
Autores principales: | Lin, Louis, Wong, Harvey |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750647/ https://www.ncbi.nlm.nih.gov/pubmed/28954416 http://dx.doi.org/10.3390/pharmaceutics9040041 |
Ejemplares similares
-
Food Effects on Oral Drug Absorption: Application of Physiologically-Based Pharmacokinetic Modeling as a Predictive Tool
por: Cheng, Lisa, et al.
Publicado: (2020) -
Predictive Performance of Physiologically Based Pharmacokinetic Models for the Effect of Food on Oral Drug Absorption: Current Status
por: Li, Mengyao, et al.
Publicado: (2017) -
Evaluating the Role of Solubility in Oral Absorption of Poorly Water‐Soluble Drugs Using Physiologically‐Based Pharmacokinetic Modeling
por: Fink, Christina, et al.
Publicado: (2019) -
Physiologically Based Pharmacokinetic Modelling of Inhaled Nemiralisib: Mechanistic Components for Pulmonary Absorption, Systemic Distribution, and Oral Absorption
por: Miller, Neil A., et al.
Publicado: (2021) -
Physiologically-Based Pharmacokinetic Modeling of PAXLOVID™ with First-Order Absorption Kinetics
por: Sagawa, Kazuko, et al.
Publicado: (2023)