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The Replication Protein Cdc6 Suppresses Centrosome Over-Duplication in a Manner Independent of Its ATPase Activity

The Cdc6 protein is essential for the initiation of chromosomal replication and functions as a licensing factor to maintain chromosome integrity. During the S and G2 phases of the cell cycle, Cdc6 has been found to inhibit the recruitment of pericentriolar material (PCM) proteins to the centrosome a...

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Detalles Bibliográficos
Autores principales: Kim, Gwang Su, Lee, Inyoung, Kim, Ji Hun, Hwang, Deog Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750711/
https://www.ncbi.nlm.nih.gov/pubmed/29237113
http://dx.doi.org/10.14348/molcells.2017.0191