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The Replication Protein Cdc6 Suppresses Centrosome Over-Duplication in a Manner Independent of Its ATPase Activity
The Cdc6 protein is essential for the initiation of chromosomal replication and functions as a licensing factor to maintain chromosome integrity. During the S and G2 phases of the cell cycle, Cdc6 has been found to inhibit the recruitment of pericentriolar material (PCM) proteins to the centrosome a...
Autores principales: | Kim, Gwang Su, Lee, Inyoung, Kim, Ji Hun, Hwang, Deog Su |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Molecular and Cellular Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750711/ https://www.ncbi.nlm.nih.gov/pubmed/29237113 http://dx.doi.org/10.14348/molcells.2017.0191 |
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